Does it make sense to thin out the polymer `js elements?

I am creating a project that uses a browser and now I would like to add polymer for custom elements. (I am using grunt for automatic builds)

Polymer is pretty stubborn about how custom elements are defined. Apparently it makes sense from a modularity point of view to have everything owned by an element in the same file.

On the other hand, browerify has to manage all javascript dependencies and code ... so my question is basically: where is optimal for large projects (like web platforms)?

Thank!