How to remove image from file list and upload it to server using api request?

I am using Html multi-select to select images and apply javascript to display images. As you can see in this figure, a cross is on top of each image, which removes the images from the user interface. So, if from the three displayed images I remove one of them and upload it to the server, it will download all three imgs instead of two images.

my script:

   $(document).on('click', '.browse', function () {
            var file = $(this).parent().parent().parent().find('.file');
            file.trigger('click');
        });
        $(document).on('change', '.file', function () {
            $(this).parent().find('.form-control').val($(this).val().replace(/C:\\fakepath\\/i, ''));
        });

        function handleFileSelect(evt) {
            var files = evt.target.files; // FileList object
            // Loop through the FileList and render image files as thumbnails.
            for (var i = 0, f; f = files[i]; i++) {
                if (i > 3) {

                    break;
                }

                                var reader = new FileReader();

                // Closure to capture the file information.
                reader.onload = (function (theFile) {
                    return function (e) {
                        // Render thumbnail.
                        var span = document.createElement('span');
                        span.innerHTML = ['<img class="thumbs_image" src="', e.target.result,
                            '" title="', escape(theFile.name), '"/> <a href="#" class="remove_pic">X</a>'
                        ].join('');
                        document.getElementById('list').insertBefore(span, null);

                        span.children[1].addEventListener("click", function (event) {
                            span.parentNode.removeChild(span);


                        });
                    };
                })(f);

                // Read in the image file as a data URL.
                reader.readAsDataURL(f);
            }
        }