Cassandra :: Unexpected exception during request; channel = [id: 0x7acf3f0c, L: /100.55.10.124: 9042! R: /30.75.50.2: 39263]

I am using Cassandra 3.10 with 6 Nodes clusters with replication factor 2. [Think IP was masked and not original.)

Datacenter: DC1
===========================================
Status=Up/Down
|/ State=Normal/Leaving/Joining/Moving
--  Address       Load       Tokens       Owns (effective)  Host ID                               Rack
UN  100.55.10.124  212.33 MiB  256          65.9%             8328123a-678c-4027-a136-06b3626ab017  rack1
UN  100.55.10.125  216.92 MiB  256          67.1%             af76123c-6880-43d6-bff8-b139731242bd  rack1
UN  100.55.10.126  216.94 MiB  256          67.0%             f541cdc1-aa2f-4a30-3612-5d4291421ec3  rack1
Datacenter: DC2
===========================================
Status=Up/Down
|/ State=Normal/Leaving/Joining/Moving
--  Address       Load       Tokens       Owns (effective)  Host ID                               Rack
UN  100.55.10.130  198.15 MiB  256          60.7%             332eb914-bf14-4d0d-9c38-47fc4b0952f1  rack2
UN  100.55.10.131  229.48 MiB  256          70.8%             cafc702f-83d4-479a-b117-ada75274e0ba  rack2
UN  100.55.10.132  223.14 MiB  256          68.5%             8a9c03ae-ed5a-4cb9-9540-0ca97a04640e  rack2

      

        
        
        
      

    

worked fine but these days i see below "INFO" in syslogs

INFO  [Native-Transport-Requests-3] 2017-04-19 03:21:19,684 Message.java:617 - Unexpected exception during request; channel = [id: 0x7acf3f0c, L:/100.55.10.124:9042 ! R:/30.75.50.2:39263]
io.netty.channel.unix.Errors$NativeIoException: syscall:read(...)() failed: Connection reset by peer
        at io.netty.channel.unix.FileDescriptor.readAddress(...)(Unknown Source) ~[netty-all-4.0.39.Final.jar:4.0.39.Final]

      

        
        
        
      

    

I tried to analyze the problem but could not do it.

I've reviewed the following JIRA around this but couldn't find anything useful.
I also referenced several stackoverflow links that couldn't find anything convincing.  

• Unexpected exception during request
• Cassandra timeouts without CPU usage
• Strange exception at /var/log/cassandra/system.log

I am using CQL v3.4.4. Is there anyone familiar with the above scenario?